Pueraria mirifica prevents bone loss ii

Bone loss is one major menopause symptom. Pueraria mirifica improves bone loss caused by estrogen deficiency.

 

J Reprod Dev. 2004 Dec;50(6):639-45.

Long-term treatment effects of Pueraria mirifica phytoestrogens on parathyroid hormone and calcium levels in aged menopausal cynomolgus monkeys.

Trisomboon H, Malaivijitnond S, Suzuki J, Hamada Y, Watanabe G, Taya K.

Biological Science Ph.D. Program, Faculty of Science, Chulalongkorn University, Bangkok, Tokyo, Japan.

PMID: 15647615 [PubMed – indexed for MEDLINE]

 

To determine the effect of Pueraria mirifica (PM) on serum parathyroid hormone (PTH) and calcium levels on aged menopausal monkeys (Macaca fascicularis), subjects were treated with 10, 100, or 1,000 mg/day of PM. Blood samples were collected every 5 days for 30, 90, and 60 days during pre-treatment, treatment, and post-treatment periods, respectively. Sera were assayed for PTH, estradiol, and calcium levels. PM-1,000 had the strongest effect on the decrease in PTH (0.001The results suggest that long-term treatment with 1,000 mg/day of Pueraria mirifica decreases serum PTH and calcium levels in aged menopausal monkeys, indicating that Pueraria mirifica ameliorates bone loss caused by estrogen deficiency.

 

Pueraria mirifica studies

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Efficacy comparison of Pueraria mirifica (PM) against conjugated equine estrogen (CEE) with/without medroxyprogesterone acetate (MPA) in the treatment of climacteric symptoms in perimenopausal women: phase III study

Pueraria mirifica reduce Breast cancer risks

Research and Study on Pueraria mirifica

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The effect of Pueraria mirifica on cytologic and urodynamic findings in ovariectomized rats.Effects and safety of Pueraria mirifica on lipid profiles and biochemical markers of bone turnover rates in healthy postmenopausal women.

Effects and safety of Pueraria mirifica on lipid profiles and biochemical markers of bone turnover rates in healthy postmenopausal women.

Long-term treatment effects of Pueraria mirifica phytoestrogens on parathyroid hormone and calcium levels in aged menopausal cynomolgus monkeys.

Pueraria mirifica, a phytoestrogen-rich herb, prevents bone loss in orchidectomized rats.

Finished herbal product as an alternative treatment for menopausal symptoms in climacteric women.

Efficacy and safety of Pueraria mirifica (Kwao Kruea Khao) for the treatment of vasomotor symptoms in perimenopausal women: Phase II Study.

Challenges in the conduct of Thai herbal scientific study: efficacy and safety of phytoestrogen, pueraria mirifica (white kwao krua) phase I, in the alleviation of climacteric symptoms in perimenopausal women.

Beneficial Estrogenic Effects of Pueraria mirifica on Vaginal Health in Postmenopausal Women

Medical Reports on the Effectiveness of Phytoestrogens 

Pueraria mirifica clinical study in Premenopausal women

Case Control Study of Phytoestrogens and Reduction in breast-cancer risk 

Pueraria mirifica (White Kwao krua ) References